Vertexyn (Nanjing) Bioworks Co., Ltd.

Factory Directly Supply Natural Product  ≥99% Protocatechuic Acid( 99-50-3) in Stock

Product Advantages:

Our products produced through bio-synthetic technology, natural purity≥98%. Our products have obtained multiple certifications such as ISO9001, HALAL, Kosher (OU), and our quality is fully guaranteed. You don't need to wait, we will supply in stock immediately, and can customize production according to your needs. Our price includes taxes and shipping services, so you don't have to worry about any worries. Choose us, and you will enjoy high-quality, cost-effective products and services.

Test Report of Natural Purity: Purity Natural >96%

Product Description: 

Protocatechuic acid, also known as 3,4-dihydroxybenzoic acid, is a type of phenolic acid and serves as a precursor for the synthesis of various complex molecules, such as cyanidin 3-O-β-D-glucoside found in plants. It is one of several isomers of dihydroxybenzoic acid. Protocatechuic acid is a primary metabolite of antioxidant polyphenols in green tea and exhibits some inhibitory effects on tumor cells. Protocatechuic acid is widely present in common medicinal herbs like Eleutherococcus senticosus, rehmannia, and Rhododendron molle. It possesses pharmacological activities, including antiplatelet aggregation, reducing myocardial oxygen consumption, enhancing myocardial tolerance to oxygen, slowing heart rate, antimicrobial properties, and analgesic effects. Moreover, protocatechuic acid exhibits antioxidant, anti-tumor, and neuroprotective properties. Using protocatechuic acid as a raw material, drugs like resveratrol, meclofenamic acid hydrochloride, berberine hydrochloride II, and itopride hydrochloride can be synthesized. Combining protocatechuic acid acid with other substances in pharmaceutical formulations can effectively reduce the time required for wound healing in diabetic foot ulcers.

Product Efficacies：

1. Anti-Cancer: Protocatechuic acid is used as a raw material to synthesize the anticancer drug Erlotinib through various reactions such as etherification and nitration.

2. Antibacterial: Protocatechuic acid has inhibitory effects on various bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae, Haemophilus influenzae, Pseudomonas aeruginosa, Escherichia coli, and Proteus vulgaris. In mice, it reduces the mortality rate caused by Staphylococcus aureus infection by 30%.

3. Expectorant and Bronchodilator: Protocatechuic acid has shown significant bronchodilatory effects in a guinea pig histamine aerosol-induced asthma test. It is clinically used to treat chronic bronchitis. In mice administered 4.68 mg of Protocatechuic acid by gastric lavage, it exhibits expectorant effects.

4. Detoxification: Protocatechuic acid has a protective effect against cobra venom poisoning in mice. It also has a significant inhibitory effect on "formalin-induced foot swelling" in mice, which is stronger than salicylic acid and close to acetylsalicylic acid.

5. Animal Feed Additive:(1) Adding Protocatechuic acid to animal feed formulas enhances the antioxidant and anti-inflammatory abilities of weaning piglets, alleviating oxidative damage caused by weaning and effectively reducing inflammatory responses and improving anemia, thus lowering piglet mortality. Protocatechuic acid can substitute antibiotics to alleviate stress-induced ailments in weaning piglets.(2) The use of a feed additive containing 0.75-3% Protocatechuic acid improves boar's spermatogenic ability, enhances sperm quality, and extends their reproductive lifespan.(3) When used in the feed of crucian carp, in conjunction with Puerarin and combined with vitamins, minerals, and heat-resistant probiotics, Protocatechuic acid improves lipid metabolism and has a significant anti-inflammatory and detoxifying effect on hepatitis and enteritis, reinforcing the overall immune system and metabolic balance of crucian carp. This results in higher weight gain, thicker dorsal muscle, and better coloration.(4) Properly dosed Protocatechuic acid in feed significantly improves the growth performance and meat quality of yellow feather broilers, enhances antioxidant capacity, improves intestinal immune function, and tightens the gut connection. It can also promote gut health by improving the gut microbiome structure, leading to better post-molt layer performance and egg quality. (5) The use of Protocatechuic acid in feed additives for ducks increases their weight by 20-25%, and the nutritional content becomes richer. (6) Silkworms exposed to organic nitrogen pesticides exhibit signs of excitement, reduced mulberry leaf consumption, and flat or erratic silk spinning. After poisoning, spraying tyrosine solution on the silkworm surface and feeding them non-toxic mulberry leaves sprayed with Protocatechuic acid can reduce the silkworm death rate from 100% (feeding non-toxic mulberry leaves only) to 0%.

6. Alternative to Bisphenol A (BPA) in New Materials: Protocatechuic acid contains hydroxyl and carboxyl functional groups that can introduce flexible segments, leading to a higher cross-linking density, improved heat stability, impact resistance, and greater elongation at break in materials, making it suitable for aerospace applications. Protocatechuic acid-modified acrylic ester resins outperform poly (methyl methacrylate) (PMMA) materials based on bisphenol A in terms of performance.

7. As a Key Ingredient for Synthesizing Vanillin (also known as Vanilla Aldehyde, with the chemical name 3-methoxy-4-hydroxybenzaldehyde): Protocatechuic acid is a primary component used in the synthesis of vanillin, a popular flavor compound used in various food and fragrance products.

Our Advantages:

1. We integrate research and development, production, and sales.A 1600 square meter highly intelligent laboratory and high-throughput screening research and development platform, as well as a 20000 square meter high standard biological intelligent manufacturing base, can ensure high-quality and fast delivery of products.A professional sales team ensures that you have no worries about pre-sales & after-sales.

2. We focus on natural products and biosynthesis technology, are specialized in the production of cosmetics raw materials, pharmaceutical raw materials & intermediates, food additives and natural pigments.

3.We supply grade products scale from gram to metric-tons ,besides,some product specifications and packaging can be customized.

4. We have rich domestic and foreign trade experience. At present, customers are all over the world, and they have received high recognition and trust in customers.

5. We can provide a variety of safe transportation methods of goods for you to choose , ensuring that products can be delivered safely, quickly, and conveniently.

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